FDA approves Tecentriq in combination with Cotellic and Zelboraf for patients with advanced skin cancer

Summary: The Food and Drug Administration (FDA) announced the approval of a new combination of three different drugs for the treatment of patients with BRAF V600 mutation-positive advanced melanoma. The new regimen combines an immunotherapy, Tecentriq (atezolizumab), with two targeted therapies, Cotellic (cobimetinib) and Zelboraf (vemurafenib).

Dr. Dan's Takeaway: Adding Tecentriq to the combination of two approved targeted therapies extended survival from 10.6 months to 15.1 months in patients with advanced melanoma with a BRAF mutation. This is the first approval of these three types of drugs used in combination, but others will soon follow.



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